• What We Do

    Leveraging Big Data, Collaboration, and Professional Development in Undergraduate Research Experiences

    Cancer Across Vertebrates

    This project focuses on the more broad center goal of analyzing cancer across the tree of life, with an emphasis on the differences in cancer risk between the Sauropsids (birds + reptiles), Amphibians, and Mammals.

    A Life History Model of Reproductive Cancer Risk

    This project plans to compile reproductive cancer prevalence for mammalian species and model the predictive power of life history traits on the patterns of reproductive cancer prevalence observed.

    Life History Trade-offs in the Emergence of Multicellularity

    This project aims to understand how a dynamic environment can allow cooperative cells to survive and thrive under changing conditions. An understanding of this mechanism can allow us to better explain how cells started to cheat, and how cancer suppression systems formed.

    Life History Framework of Therapeutic Resistance

    The primary objective of this project is to work with the adaptive therapy gene expression and exome sequencing dataset. The goal is to determine the life history strategies for cancer cells under different modalities of cancer treatment based on the expression of growth factors, immune blockade, and angiogenic factors.

    Sex Bias in Cancer Risk Across Species

    This project focuses on the role sexual dimorphism plays in cancer prevalence across species.

    The Patient Guidance Project

    This project will focus on information that will be pertinent to patients recently diagnosed with cancer. Members of this project will choose a type of cancer that interests them and will work on creating a guide for patients that outlines what to expect after their diagnosis, treatment options, and more, along with studies that support the information. These guides are intended to educate patients after their diagnosis, which is often a confusing and frightening time, and to give them the information they need to make the important decisions they’ll be faced with.

    The Language of Cancer

    This project seeks to understand how do we talk, or not, about cancer and what implications does that have for patients, families and various interactions and outcomes, such as doctor-patient interactions, choosing a course of treatment, and more.

    Cancer-like Phenomena in Coral

    The coral cancer project aims to obtain whole genome sequencing from abnormal and neighboring normal samples from the Acropora genus and test if nearby growth abnormalities are clonal, and therefore transmissible cancers.

    Age as a Cancer Risk Factor in Nonhuman Species

    Age is the single biggest risk factor for cancer in humans so most of this work will emphasize if it is as significant a risk factor in non-human animals. This project will implement common human cancer models such as Kaplan-Meier curves to our animal cancer data.

    Outreach & Community Engagement

    The purpose of this project is to engage in science communication and outreach efforts with the purpose of translating scientific findings into everyday knowledge that reaches a broad audience, from children at the elementary school level to various communities.

    Comparative Phylogenetic Methods Development

    The purpose of this project is to call on single nucleotide variants from groups of samples sequenced at low depth.

    Diet, Microbiome, and Cancer

    The purpose of this project is to look at how diet and the microbiome affect cancer progression.

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